Is your birth control causing vitamin deficiencies? Find out

Erica Digap, Maurice Beer M.D.
April 25th, 2022 · 5 min read
Medically Verified
For many people, taking hormonal birth control is an empowering and routine part of maintaining a healthy sex life, preventing unplanned pregnancies, alleviating painful period symptoms, managing migraines, and much more. But for all the proven benefits that come with taking birth control, there is also plenty of controversy surrounding its potential long-term health effects. 

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Does birth control deplete vitamins?

Birth control, or contraception, comes in many different forms. Besides “barrier” contraception like condoms that can physically block sperm from fertilizing an egg, there are also plenty of other options that can be taken orally, inserted, implanted, or administered via shot. These types of birth control rely on hormones, which can have wide-ranging effects in your body beyond your reproductive system. This has led to questions about how they can affect the levels of nutrients in your body, specifically, vitamin B and vitamin D.
Keep in mind, though, that nutrient levels can be multifaceted issues. Yes, studies have shown that birth control can deplete certain vitamins and minerals in blood tests. However, it’s also important to keep in mind that someone’s overall nutrition status, as dictated by their eating habits, lifestyle factors, and more, also matters. For example, if you’re already getting a sufficient amount of folate from your diet, a slight decrease in folate by birth control may not put you into a “deficient status.” On the other hand, if you’re already at risk for a nutrient deficiency because you aren’t eating an adequate diet, birth control can make the situation worse.
One study on the nutritional needs of people taking oral birth control concluded that dietary supplements should be considered if people who are taking birth control are not also eating a well-balanced diet. This is why it’s so important to get your own vitamins and minerals tested: your needs are highly personal and affected by many different factors.
With that said, here’s the evidence that taking hormonal birth control can affect your Vitamin B and Vitamin D levels. 

Vitamin B deficiency

B vitamins are a group of 8 water-soluble nutrients that play a ton of important roles throughout your body. While not all 8 B vitamins are proven to be affected by hormonal birth control, it’s still been linked to deficiencies of specific vitamins in the B-vitamin complex, starting in research dating all the way back to the 70’s.
  • B2 (riboflavin) -  Vitamin B2 plays important roles in your metabolism, growth, and energy production. A study that examined the B2 levels of women in a similar socioeconomic background (and therefore similar access to food) found that the women in the study taking oral contraceptives were more likely to a riboflavin deficiency.
  • B6 - Vitamin B6 is another important nutrient for metabolism, immune health, and brain function, and several studie have shown that vitamin B6 levels tend to be lower in populations of people who take birth control.
  • B9 (folic acid) - Taking birth control can also lower your levels of folate, the natural version of folic acid. This is especially pertinent since folate is a necessity for neural development in babies, and indicates that people of child-bearing age who can get pregnant should be taking folic acid along with birth control just in case.
  • B12 - People taking birth control also show lower levels of serum B12, an essential vitamin that’s important for a variety of functions like forming red blood cells and maintaining a healthy nervous system. 

Vitamin D deficiency

Vitamin D, also known as the “sunshine vitamin,” is a hormone as well as a vitamin, so it brings up some interest in how it can interact with hormonal birth control methods.
But here’s what’s interesting about Vitamin D: while taking birth control doesn’t seem to have a detrimental effect on your Vitamin D levels (in fact, it’s actually the opposite), deciding to stop taking your birth control might present its own set of issues. Estrogen-based birth control can actually increase your Vitamin D levels. But in the same vein, it seems that people who stop taking hormonal birth control begin to see a drop in their Vitamin D levels as a result. So if you decide to stop birth control and start trying to have a baby, you may need to check in with your vitamin D levels after stopping your birth control use.

How different forms of birth control impact nutrients

Many of the studies surrounding the effects of birth control on vitamin levels were done by examining oral contraceptives (aka “the pill”), which contains the two hormones estrogen and progesterone. Other types of contraception, the vaginal ring NuvaRing, also use a combination of both estrogen and progesterone, although at least one study concluded that folate and B12 status weren’t impacted by the vaginal ring.
But estrogen/progesterone forms of contraception aren’t the only forms of contraception, and there aren’t too many studies that investigate how other types of birth control can affect your nutrient levels.
For example, let’s look at a different kind of oral contraceptive: the progestin-only pill. Some people choose to take a progestin-only birth control pill, sometimes called the “mini-pill,” to avoid the potential side-effects of estrogen, and there isn’t a whole lot of research about how the introduction of this single hormone could potentially change your dietary needs. Iin fact, the National Institutes Of Health suggest that you stick to your regular diet unless otherwise instructed by your doctor while on the mini-pill.
Similarly, other popular methods of birth control like the Depo shot, Nexplanon implants, and hormonal IUDs (intrauterine device) also use progestin on its own, not estrogen. So there isn’t much evidence that this would affect your Vitamin D levels, for example, since the deficiency seems to be driven by estrogen and not progestin.
But interestingly, the copper IUD, a birth control method that doesn’t involve any hormones at all, might be implicated in an iron deficiency, since you tend to bleed more with a copper implant and lose more iron along the way! 

Can taking vitamins or supplements interfere with birth control?

So we’ve gone over how birth control can interfere with vitamin levels. Now, let’s look at the other side of the coin: can taking certain dietary supplements interfere with the effectiveness of your birth control?
It’s a common misconception that taking biotin, aka Vitamin B7, can make your birth control less effective. This might stem from the fact that biotin supplements can interfere with testing levels of your thyroid hormones. But when it comes to birth control, there’s no evidence that taking biotin supplements can make your contraception any less effective.
There also tends to be some concern around taking supplements with phytoestrogens, a plant-based compound that can mimic the effects of estrogen in the body. Since it can hypothetically affect the amount of estrogen-like activity in your body, it also brings up the question of whether or not certain phytogen-rich supplements and foods like flaxseed and soy-based protein can interfere with your birth control. But to date, there’s no strong evidence that this should be the case.
However, things that have been proven to interfere with birth control include:
  • St John’s wort - This herbal remedy has been used for a variety of mental health ailments like depression. But it’s also known to interact with a variety of medications, including birth control, presumably because it can speed up the body’s metabolism of the hormones involved.
  • Medications - Certain medications (not supplements) have also been shown to interfere with the effectiveness of hormonal birth control. Most notably is the antibiotic rifampin. While it’s another common myth that taking antibiotics of any kind could make your birth control ineffective, rifampin is the only one that has been proven to have any effect.
At the end of the day, birth control is a medication, and medications can interact with a variety of dietary staples, vitamins, minerals, and other medications. Talking to your doctor about any current medications or supplements you take is important for ensuring your birth control will be effective. 

Bottom line

Your nutrition status is influenced by a variety of factors including your diet, lifestyle, health status, and, yes, birth control usage. Nutrient deficiencies can also go relatively undetected until they spiral into more serious issues. So when you’re taking birth control (and even when you are not), getting your nutrient levels tested is an excellent way to determine what else is going on inside of your body. Checking in with a health professional, talking to a dietitian about your dietary needs, and keeping a regular eye on your vitamin levels with an at-home testing option like Base Diet Testing can help you determine whether or not your birth control is affecting your nutrition status.

Worried about vitamin deficiencies?

Take our quiz to build a bespoke testing plan that will help you understand your nutrient levels and overcome them for optimal health.

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