Unlocking the Link Between Female Hormones and Mental Health

Base Science Team, Maurice Beer M.D.
March 14th, 2023 · 4 min read
Medically Verified
Mental health is a complex issue, affected by a variety of factors such as genetics, environment, and lifestyle. However, one factor often overlooked is hormones’ role in mental health, particularly in women. In this blog post, we will explore the connection between female hormones and mental health, and provide some tips for maintaining good mental health.
There are two key female hormones involved in brain functioning, that can also be comfortably measured at home.
Estrogen is a hormone that plays a critical role in developing and regulating female reproductive processes. It is produced mainly by the ovaries, but the adrenal glands and fat cells also produce smaller amounts. Estrogen levels fluctuate throughout a woman’s life, rising during puberty and falling during menopause. Estrogen is responsible for a wide range of physiological processes, including regulating the menstrual cycle, promoting the growth and maintenance of the reproductive organs, and maintaining healthy bones and cardiovascular function. Estrogen also affects the brain and nervous system  and is involved in regulating mood, cognitive function, and sexual behavior. When estrogen levels are out of balance, it can lead to various health issues, including irregular menstrual cycles, infertility, osteoporosis, and mood disorders such as depression and anxiety.
Progesterone is another hormone that plays an important role in the female reproductive system. It is produced by the ovaries and helps to regulate the menstrual cycle, prepare the uterus for pregnancy, and maintain a healthy pregnancy. Progesterone also affects the brain and nervous system, and has been linked to changes in sleep patterns, irritability, and anxiety. During the menstrual cycle, progesterone levels rise after ovulation and fall if pregnancy does not occur. In addition to its role in reproduction, progesterone is involved in a variety of physiological processes, including regulating blood sugar levels, maintaining healthy bones, and supporting cardiovascular health. When progesterone levels are out of balance, it can lead to various health issues, including irregular menstrual cycles, infertility, and mood disorders.

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How are female hormones linked to mental health?

Imbalances in these hormones can lead to a range of mental health issues: Here are some examples of how each of them affects emotions and mental health.

Estrogen:

Progesterone:

  • Affects sleep patterns and can cause insomnia or disrupted sleep
  • Fluctuations can lead to irritability and mood swings, particularly during the luteal phase of the menstrual cycle
  • Progesterone can also cause anxiety, particularly in women who are sensitive to hormonal changes
  • Low levels of progesterone have been linked to depression and can exacerbate symptoms of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD)
  • Progesterone can also affect gamma-aminobutyric acid (GABA) levels affect gamma-aminobutyric acid (GABA) levels, a neurotransmitter that helps regulate anxiety.
It’s important to note that the effects of estrogen and progesterone on mental health can vary widely depending on the individual and their hormonal levels. Some women may experience severe mood swings or depression during hormonal changes, while others may have few or no symptoms at all.
Mental health first pic

Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD)

PMS and PMDD are conditions that affect some women affect some women in the days leading up to their menstrual period. PMS is a group of physical and emotional symptoms that can include bloating, breast tenderness, mood swings, irritability, and fatigue. These symptoms can range from mild to severe and can vary from month to month.
PMDD is a more severe form of PMS that affects a smaller percentage of women. It includes many of the same symptoms as PMS but to a greater degree, and can also include severe depression, anxiety, and anger. PMDD can be so severe that it can interfere with a woman’s ability to function in her daily life.
Both PMS and PMDD are thought to be related to changes in hormone levels that occur during the menstrual cycle. While there is no cure for PMS or PMDD, there are many treatments available to help manage symptoms. These can include lifestyle changes like exercise and diet, as well as medications like antidepressants or hormonal birth control, in the next section we will deep dive into these treatment and prevention tips.

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Tips for Good Mental Health during Hormonal Changes

Research has shown that maintaining good mental health during hormonal changes is crucial for women’s overall well-being. Some tips that have been suggested by scientific studies and literature include:
  1. Regular exercise: Exercise has been shown to be an effective way to regulate hormones and improve mood. Studies have found that physical activity can help reduce symptoms of depression and anxiety in women, as well as improve overall well-being.
  2. Healthy diet: Eating a balanced and nutritious diet is also important for hormonal health and mental well-being. Research has found that certain nutrients, such as omega-3 fatty acids and B vitamins, can help regulate mood and reduce symptoms of depression and anxiety.
  3. Adequate sleep: Getting enough sleep is crucial for hormonal health and mental well-being. Studies have shown that sleep deprivation can lead to hormonal imbalances and increase the risk of mental health issues such as depression and anxiety.
  4. Mindfulness practices: Mindfulness practices such as meditation and yoga have been found to be helpful for managing stress and anxiety. These practices can help regulate hormones and improve mood, as well as reduce symptoms of depression and anxiety.
In conclusion, the link between female hormones and mental health is often overlooked, yet it plays a critical role in regulating mood and cognitive function. As we have seen, there are a lot of easy ways to help your body maintain a balanced hormone development avoiding common health issues like PMS and PMDD. It is also important to note that at-home hormone testing is now available to help women track and improve their hormone levels comfortably, giving them better control over their hormonal health. Therefore, by taking care of their hormonal health, women can improve their mental health and overall well-being.
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